Disable any mods added and start a “new” save to see if the issue occurs on a brand new game. Most crashing issues are related to a corrupted save and/or a bad mod being added to your game. You can try to avert these issues by setting the boundary to use only 2 cores. Press the Windows key and E at the same time to open File Explorer. How can I fix Fallout: New Vegas crashing or freezing? How do I stop Fallout New Vegas from freezing?
How do I stop Fallout New Vegas from freezing?.